- - Decision reversal ... or, literally, what can be found inside 17-, 22-, 49- and 58-Across
- - 79-Across?
- - the result of a cardiac transplant?
- - different opinion on transplant
- - altered outlook
- - Jodi Picoult novel about a man on trial for murder who wishes to make a life-saving organ donation (3 wds.)
- - Profound shift in outlook
- - 2008 Jodi Picoult novel ... or a hint to the puzzle theme
- - Attitude reversal
- - Jodi Picoult book
- - Replace the organ or get a second opinion
- - Earth-shattering volte-face?
- - Shift in attitude
- - Transplant earth?
- - What could be Earth's second 5
- - Revision of attitude that's produced by major operation
- - Altered attitude that could make son sin?
- - Option of theatre shift work if you've a mind to do something different
- - Decision alteration
- - Reaction to a persuasive argument, perhaps
- - Cardiologist's drastic remedy?
- - Conversion
- - Reversal in attitude.
- - Second thoughts
- - Earth ....
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